Immunologist Derya Unutmaz used GPT-5 to crack a three-year-old puzzle about how glucose affects T cells, which could lead to breakthroughs in cancer, autoimmune disease, and infection research. The model helped Unutmaz understand how T cells develop and specialize, and the findings have significant implications for human health. Unutmaz’s experience showcases the potential of AI to augment human expertise in scientific research, and he now considers AI essential to his work. Why it matters: this story highlights the vast potential of AI to accelerate medical discoveries and improve human health.